Reset
Start Over
Help
Publication Permission Requests
Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
MLN-518
Highlight These Spots (
fill
):
MLN-518|ACVR1|2500
MLN-518|AURKB|1700
MLN-518|AURKC|1600
MLN-518|AXL|6300
MLN-518|CDK7|3100
MLN-518|CDKL2|2900
MLN-518|CLK1|630
MLN-518|CLK2|6500
MLN-518|CLK3|6600
MLN-518|CLK4|1600
MLN-518|CSF1R|4.9
MLN-518|DDR1|1400
MLN-518|DDR2|120
MLN-518|EGFR|410
MLN-518|EPHB6|1300
MLN-518|FLT1|3100
MLN-518|FLT3|3
MLN-518|FLT4|7200
MLN-518|GAK|3700
MLN-518|HIPK4|2400
MLN-518|IRAK1|2700
MLN-518|IRAK3|730
MLN-518|KIT|2.7
MLN-518|LCK|7200
MLN-518|LOK|9500
MLN-518|MAP4K5|780
MLN-518|MEK5|3100
MLN-518|MERTK|3500
MLN-518|PCTK1|6000
MLN-518|PDGFRA|2.4
MLN-518|PDGFRB|4.5
MLN-518|PLK4|7600
MLN-518|SRC|9600
MLN-518|TRKA|450
MLN-518|TRKB|740
MLN-518|TRKC|2000
MLN-518|YSK4|5900
MLN-518|ACVR1
MLN-518|AURKB
MLN-518|AURKC
MLN-518|AXL
MLN-518|CDK7
MLN-518|CDKL2
MLN-518|CLK1
MLN-518|CLK2
MLN-518|CLK3
MLN-518|CLK4
MLN-518|CSF1R
MLN-518|DDR1
MLN-518|DDR2
MLN-518|EGFR
MLN-518|EPHB6
MLN-518|FLT1
MLN-518|FLT3
MLN-518|FLT4
MLN-518|GAK
MLN-518|HIPK4
MLN-518|IRAK1
MLN-518|IRAK3
MLN-518|KIT
MLN-518|LCK
MLN-518|LOK
MLN-518|MAP4K5
MLN-518|MEK5
MLN-518|MERTK
MLN-518|PCTK1
MLN-518|PDGFRA
MLN-518|PDGFRB
MLN-518|PLK4
MLN-518|SRC
MLN-518|TRKA
MLN-518|TRKB
MLN-518|TRKC
MLN-518|YSK4
MLN-518|ACVR1|2500
MLN-518|AURKB|1700
MLN-518|AURKC|1600
MLN-518|AXL|6300
MLN-518|CDK7|3100
MLN-518|CDKL2|2900
MLN-518|CLK1|630
MLN-518|CLK2|6500
MLN-518|CLK3|6600
MLN-518|CLK4|1600
MLN-518|CSF1R|4.9
MLN-518|DDR1|1400
MLN-518|DDR2|120
MLN-518|EGFR|410
MLN-518|EPHB6|1300
MLN-518|FLT1|3100
MLN-518|FLT3|3
MLN-518|FLT4|7200
MLN-518|GAK|3700
MLN-518|HIPK4|2400
MLN-518|IRAK1|2700
MLN-518|IRAK3|730
MLN-518|KIT|2.7
MLN-518|LCK|7200
MLN-518|LOK|9500
MLN-518|MAP4K5|780
MLN-518|MEK5|3100
MLN-518|MERTK|3500
MLN-518|PCTK1|6000
MLN-518|PDGFRA|2.4
MLN-518|PDGFRB|4.5
MLN-518|PLK4|7600
MLN-518|SRC|9600
MLN-518|TRKA|450
MLN-518|TRKB|740
MLN-518|TRKC|2000
MLN-518|YSK4|5900
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
MLN-518
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
MLN-518
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\659_jjn5gatsv2ek5ceo44zik2m1\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
MLN-518
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
ACVR1
AURKB
AURKC
CDKL2
CLK1
CLK4
CSF1R
DDR1
DDR2
EGFR
EGFR
EPHB6
FLT3
FLT3
HIPK4
IRAK1
IRAK3
KIT
KIT
MAP4K5
PDGFRA
PDGFRB
TRKA
TRKB
TRKC
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
Copyright © 2005-2012 KINOMEscan, a division of DiscoveRx Corp. All Rights Reserved.